Presentation[ edit ] The symptoms of the inherited form of ichthyosis vulgaris are not usually present at birth but generally develop between 3 months and 5 years of age.
References Takeichi T, Akiyama M. Ichthyosis vulgaris - the filaggrin mutation disease. Linkage analysis suggests a locus of ichthyosis vulgaris on 1q Identification of a genetic locus for ichthyosis vulgaris on chromosome 10q Evolving concepts of pathogenesis in atopic dermatitis and other eczemas.
Filaggrin genotype determines functional and molecular alterations in skin of patients with atopic dermatitis and ichthyosis vulgaris. Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema.
Eur J Hum Genet. Novel FLG mutations associated with ichthyosis vulgaris in the Chinese population. Targeted Icthyosis vulgaris sequencing identifies 9 novel FLG variants in Chinese Han patients with ichthyosis vulgaris.
Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis. J Allergy Clin Immunol. Specific filaggrin mutations cause ichthyosis vulgaris and are significantly associated with atopic dermatitis in Japan.
FLG mutations in ichthyosis vulgaris and atopic eczema: Complete filaggrin deficiency in ichthyosis vulgaris is associated with only moderate changes in epidermal permeability barrier function profile. J Eur Acad Dermatol Venereol. Paraneoplastic Addisonian pigmentation and acquired ichthyosis as presenting features of multiple myeloma.
J Coll Physicians Surg Pak. Two unusual skin manifestations of systemic lupus erythematosus. Acquired ichthyosis triggered by an osseous hemangiopericytoma: London RD, Lebwohl M.
Acquired ichthyosis and hyperparathyroidism. J Am Acad Dermatol. Acquired ichthyosis in bone marrow transplant recipients.
Acquired ichthyosis associated with an overlap syndrome of systemic sclerosis and systemic lupus erythematosus.
Acquired ichthyosis associated with dermatomyositis. Dermatomyositis and acquired ichthyosis as paraneoplastic manifestations of ovarian tumor. Reduction of serum cholesterol levels and beta-lipoprotein cholesterol levels by nicotinic acid.
Ichthyosis induced by cholesterol-lowering drugs. Implications for epidermal cholesterol homeostasis. Hair loss, depigmentation of hair, ichthyosis, and blepharoconjunctivitis produced by dixyrazine. Clofazimine-induced ichthyosis and its treatment.
Bathing suit ichthyosis is caused by transglutaminase-1 deficiency: Sebaceous gland, hair shaft, and epidermal barrier abnormalities in keratosis pilaris with and without filaggrin deficiency.Ichthyosis is one of the most frequent single-gene disorders in humans.
The most widely cited incidence figure is 1 in based on a survey of 6, healthy English schoolchildren (Wells and Kerr, ).The phenotypic characteristics of ichthyosis vulgaris include palmar hyperlinearity, keratosis pilaris, and a fine scale that is most prominent over the lower abdomen, arms, and legs.
The Interactive Dermatology Atlas web site does not define a standard of care, nor is it intended to dictate an exclusive course of diagnosis, treatment or management. Ichthyosis vulgaris is an inherited or acquired skin condition that occurs when the skin doesn’t shed its dead skin cells.
This causes dry, dead skin cells to accumulate in patches on the surface of the skin. homo sapiens diseases - cutaneous apparatus and subcutaneous tissue. table of contents. Telegraph Road, Suite , Bingham Farms, Michigan (USA).
Ichthyosis is a skin condition that leaves the skin scaly, flakey or with dry, cracked skin. It affects about 1 in people worldwide.
Although most cases are a mild .